Research interest
The Research Group of Biological Nanochemistry was established in 2009 with the aim of connecting the traditional colloid chemistry with the new challenges in biology and medicine. The primary task of the Research Group is the synthesis of nanosized systems for medical applications including the modification of nanostructures, their characterization from the atomic level up to the µm range, optimization for biological and medical applications, and preliminary toxicity investigation in cell cultures and small animals.
Homepage of the Biological Soft Matter Platform
Homepage of the Small-Angle X-ray Scattering Infrastructure
Primary research areas
- Preparation and surface modification of organic and inorganic nanosystems
- Investigation of the structure and dynamics of model membrane systems (focusing to uni- and multilamellar vesicles), and of their interactions with drugs and other molecules of biological importance
- Development of nanostructures for the targeted delivery of drugs and sensor molecules
- Investigation of the biological activity and toxicity of the nanosystems prepared
Projects
- Synthesis and characterization of surface modified organic and inorganic nanosystems for targeted delivery of drugs and sensor molecules (principal investigator:Lívia Naszályi Nagy Ph.D., Marcell Pálmai Ph.D. student, Balázs Söptei Ph.D. student)
- Structural and morphological study and separation of complex nanosystems (focusing to model membrane systems, e.g. uni- and multilamellar vesicles), and to their interactions with drugs and sensor molecules (principal investigator: Zoltán Varga Ph.D., Attila Bóta D.Sc., Teréz Kiss, Tibor Kremmer D.Sc., András Wacha Ph.D. student, István Gyurkó M.Sc. student)
- Spectroscopy of molecular interactions in complex nanosystems (principal investigator: Judith Mihály Ph.D., Sándor Kristyán Ph.D., Csaba Németh, Imola Szigyártó Ph.D.)
- Localization and distribution in biological media (cells, tissue of small animals) of the nanosystems prepared by the Group (principal investigator: Attila Bóta D.Sc., Róbert Deák Ph.D. student, Teréz Kiss, András Lőrincz Ph.D. student)
Leader
Zoltán Varga